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Synthesis of sesquiterpene antitumor lactones. 7. Studies directed toward the total synthesis of pentalenolactone. Intramolecular ene reaction.

✍ Scribed by Frank Plavac; Clayton H. Heathcock


Book ID
108384816
Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
147 KB
Volume
20
Category
Article
ISSN
0040-4039

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Studies directed towards the asymmetric
✍ Kiyoshi Tomioka; Hidemichi Mizuguchi; Kenji Koga πŸ“‚ Article πŸ“… 1978 πŸ› Elsevier Science 🌐 French βš– 205 KB

Some biologically potent natural lignans having bis-benzylbutyrolactone skeleton, steganacin (s', podophyllotoxin (z2, (-)-trans-2-(3,4,5\_trimethoxy benzyl)-3-(3,4-methylenedioxybenzyl)butyrolactone (3)', are known to be optically rV active. Interestingly steganacin has the absolute configuration o