𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of (S)-mappicine and mappicine ketone via radical cascade reaction of isonitriles

✍ Scribed by Hubert Josien; Dennis P. Curran

Book ID
108378910
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
565 KB
Volume
53
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis of (+/-) mappicine and mappici
Synthesis of (+/-) mappicine and mappicine ketone
✍ Kevin E. Henegar; Ted A. Baughman πŸ“‚ Article πŸ“… 2003 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 46 KB

## Abstract Mappicine and mappicine ketone are camptothecin analogs of interest as antiviral agents. A novel synthesis of these compounds is described using a Friedlander condensation. The requisite ketone is prepared __via__ a regioselective __ortho__‐directed metallation/alkylation of a trisubsti