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Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6-cd]indole-8,10-diones

✍ Scribed by Siavosh Mahboobi; Stella Eluwa; Markus Koller; Alfred Popp; Dieter Schollmeyer

Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
679 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

3‐Amino‐4‐(3‐indolyl)pyrrolin‐2,5‐diones are condensed with various aldehydes and ketones to the cor responding imines. Under Pictet‐Spengler conditions, the latter do not cyclize to pyrrolo‐β‐carbolines, but readily yield pyrrolo[3′,4′:2,3]azepino[4,5,6‐cd]indole‐8,10‐diones.

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