𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of pyridylglyoxylic acid derivatives via a palladium-catalysed double carbonylation of iodopyridines

✍ Scribed by Samuel Couve-Bonnaire; Jean-François Carpentier; Yves Castanet; André Mortreux

Book ID
104261379
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
112 KB
Volume
40
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

4-Iodopyridines react with CO and HNEt 2 or 2-BuOH/NEt 3 in the presence of a catalytic amount of PdCI2(-PPh3)2 to give the corresponding a-keto amides and esters in fair to high yields.

📜 SIMILAR VOLUMES

Synthesis of quinol-4-ones and chroman-4
Synthesis of quinol-4-ones and chroman-4-ones via a palladium-catalysed cascade carbonylation–allene insertion
✍ Ronald Grigg; Angela Liu; Duncan Shaw; Selvaratnam Suganthan; Diane E Woodall; G 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 218 KB

Palladium(0)-catalysed termolecular queuing processes involving oxidative addition to aryl iodides followed by low pressure carbonylation, allene insertion and capture of the resulting p-allyl palladium(II) species by an internal O-or N-nucleophile occur in good yields. One-pot 3-methylene chromanon