Synthesis of pyridylglyoxylic acid deriv
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Samuel Couve-Bonnaire; Jean-François Carpentier; Yves Castanet; André Mortreux
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Article
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1999
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Elsevier Science
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French
⚖ 112 KB
4-Iodopyridines react with CO and HNEt 2 or 2-BuOH/NEt 3 in the presence of a catalytic amount of PdCI2(-PPh3)2 to give the corresponding a-keto amides and esters in fair to high yields.