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Synthesis of Pyrido[2,3- e ]pyrrolo[1,2- a ]pyrazine Derivatives via Tandem Iminium Cyclization and Smiles Rearrangement

✍ Scribed by Xiang, Jinbao; Xie, Hongxiang; Wen, Dongsheng; Dang, Qun; Bai, Xu


Book ID
126837977
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
54 KB
Volume
73
Category
Article
ISSN
0022-3263

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## Abstract The synthesis of the title compounds was achieved using the key intermediate ethyl 4,6‐dimethyl‐3‐(pyrrol‐1‐yl)thieno[2,3‐__b__]pyridine‐2‐ carboxylate 2. This latter compound was obtained __via__ the interaction of the thienopyridine amino ester 1 with 2,5 dimethoxytetrahydrofuran in a