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New fused pyrazines. Synthesis of pyrido[3′,2′:4,5]-thieno[2,3-e]pyrrolo[1,2-a]pyrazine derivatives

✍ Scribed by H. S. El-Kashef; A. M. Kamal El-Dean; A. A. Geies; J. C. Lancelot; P. Dallemagne; S. Rault

Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
398 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

The synthesis of the title compounds was achieved using the key intermediate ethyl 4,6‐dimethyl‐3‐(pyrrol‐1‐yl)thieno[2,3‐b]pyridine‐2‐ carboxylate 2. This latter compound was obtained via the interaction of the thienopyridine amino ester 1 with 2,5 dimethoxytetrahydrofuran in acidic medium.

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