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Synthesis of pyrazole, isoxazole, and pyrimidine derivatives from 2-arylsulfonyl-2-cyanovinyl ethyl ethers

โœ Scribed by V. M. Neplyuev; T. A. Sinenko; P. S. Pel'kis


Book ID
112326423
Publisher
Springer US
Year
1978
Tongue
English
Weight
256 KB
Volume
14
Category
Article
ISSN
0009-3122

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Heterocyclic synthesis via enaminones: R
โœ Kamal M. Dawood; Zaghloul E. Kandeel; Ahmad M. Farag ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 164 KB ๐Ÿ‘ 2 views

## 2-Acetylbenzothiazole (1) reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the enaminone 2. Compound 2 reacts regioselectively with some nitrilimines 5a-d and nitrile oxides 6b-d to afford the novel pyrazole and isoxazole derivatives 11a-d and 12b-d, respectively, which react wi