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Heterocyclic Synthesis via Enaminonitriles: One-pot Synthesis of Some New Pyrazole, Isoxazole, Pyrimidine, Pyrazolo[1,5-a]pyrimidine, Pyrimido[1,2-a]benzimidazole and Pyrido[1,2-a]benzimidazole Derivatives

✍ Scribed by Dawood, Kamal M.; Farag, Ahmad M.; Kandeel, Zaghloul E.


Book ID
120221041
Publisher
Science Reviews 2000 Ltd
Year
1999
Tongue
English
Weight
161 KB
Volume
2
Category
Article
ISSN
0308-2342

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Heterocyclic synthesis via enaminones: R
✍ Kamal M. Dawood; Zaghloul E. Kandeel; Ahmad M. Farag πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 164 KB πŸ‘ 2 views

## 2-Acetylbenzothiazole (1) reacts with dimethylformamide dimethylacetal (DMF-DMA) to afford the enaminone 2. Compound 2 reacts regioselectively with some nitrilimines 5a-d and nitrile oxides 6b-d to afford the novel pyrazole and isoxazole derivatives 11a-d and 12b-d, respectively, which react wi