✦ LIBER ✦

Synthesis of potential antimalarials: Primaquine analogs

✍ Scribed by S. M. Talati; M. R. Latham; E. G. Moore; G. W. Hargreaves; C. Dewitt Blanton Jr.

Publisher: John Wiley and Sons
Year: 1970
Tongue: English
Weight: 575 KB
Volume: 59
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600590411

No coin nor oath required. For personal study only.

✦ Synopsis

A series of 8-aminoquinolines, analogous to primaquine and carrying a substituent in position two, have been synthesized by standard methods and tested for activity against Plas- modium berghei in mice. The results of preliminary biological tests are reported.

📜 SIMILAR VOLUMES

4, 5-Disubstituted primaquine analogs as

4, 5-Disubstituted primaquine analogs as potential antiprotozoan agents

✍ Hanns Burghard; C. Dewitt Blanton Jr. 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 522 KB

Synthesis of site specifically deuterate

Synthesis of site specifically deuterated primaquines I. Quinoline ring deuterated primaquines

✍ James D. McChesney; Srinivasan Sarangan 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 394 KB

## Abstract Site specific deuterated primaquines were prepared. The attempts to prepare these by deuterolysis of bromoprimaquines were unsuccessful because the required bromoprimaquines could not be produced satisfactorily by alkylation of the various bromo‐6‐ methoxy‐8‐aminoquinolines. Instead pri

Synthesis of site specifically deuterate

Synthesis of site specifically deuterated primaquines II. N-alkyl deuterated primaquines

✍ James D. McChesney; Srinivasan Sarangan 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 278 KB

## Abstract Two site specifically deuterated primaquines were prepared. 4′,4′‐Dideutero primaquine **3** was obtained from the corresponding dideutero alcohol which was prepared by the low temperature reduction of the ester compound **4** with lithium aluminium deuteride. 1′‐Deutero primaquine r wa

Synthesis of novel pyrazolopyrrolopyrazi

Synthesis of novel pyrazolopyrrolopyrazines, potential analogs of sildenafil

✍ Marina Kopp; Jean-Charles Lancelot; Patrick Dallemagne; Sylvain Rault 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 62 KB

## Abstract Synthesis of novel pyrazolopyrrolopyrazines is herein described with the aim to reach new specific PDE‐5 inhibitors of potential clinical interest in male erectile dysfunction.

Synthesis of sparsomycin analogs as pote

Synthesis of sparsomycin analogs as potential antitumor agents

✍ R. J. Dubois; C.-C. L. Lin; B. L. Michel 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 421 KB

Synthesis and Evaluation of Febrifugine

Synthesis and Evaluation of Febrifugine Analogues as Potential Antimalarial Agents.

✍ Shuren Zhu; Li Meng; Quan Zhang; Lai Wei 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 12 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.