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Synthesis of potential agonists and antagonists for central glutamate receptors by a novel ?ring switching? process

✍ Scribed by Bowler, Andrew N.; Doyle, Paul M.; Young, Douglas W.


Book ID
111689044
Publisher
The Royal Society of Chemistry
Year
1991
Tongue
English
Weight
273 KB
Volume
5
Category
Article
ISSN
0022-4936

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The activated b-lactam aldehydes 31 and 55 were synthesised and found to be excellent substrates for our 'ring switching' strategy for preparation of libraries of homochiral compounds with potential for activity at specific glutamate receptor sub-types. The product heteroaromatic glycine derivatives