Synthesis and Structure−Activity Relationship of a Novel Series of Aminoalkylindoles with Potential for Imaging the Neuronal Cannabinoid Receptor by Positron Emission Tomography
✍ Scribed by Pavlova, Olga A.; Chefer, Svetlana I.; Vaupel, D. Bruce; Mukhin, Alexey G.; Horti, Andrew G.; Willis, Peter G.
- Book ID
- 115484628
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 370 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The novel 2-mercaptoimidazole derivatives, 1-[4-((2-methoxyphenyl)-1-piperazinyl)butyl]-2-mercaptoimidazole (3) and methyl[4-((2-methoxyphenyl)-1-piperazinyl))butyl] (2-mercapto-1-methylimidazol-5-yl)methanamide ( 8), were efficiently labelled with 11 C through methylation of the thioketone function
## Abstract __ω__‐Conotoxin GVIA is a potent, irreversible antagonist of __N__‐type voltage gated Ca^2+^ channels. A radiofluorinated analogue of GVIA could be useful in assessing regional synaptic density of the brain, __in vivo__, using positron emission tomography. __N__‐hydroxy succinimidyl 4‐[