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Synthesis of Polysubstituted Isoquinolines through Cross-Coupling Reactions with α-Alkoxytosylhydrazones

✍ Scribed by Florentino, Lucía; Aznar, Fernando; Valdés, Carlos

Book ID
118020783
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
458 KB
Volume
14
Category
Article
ISSN
1523-7060

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A series of α-(fluoro-substituted phenyl)pyridines have been synthesized by means of a palladium-catalyzed cross-coupling reaction between fluoro-substituted phenylboronic acid and 2-bromopyridine or its derivatives. The reactivities of the phenylboronic acids containing di-and tri-fluoro substituen