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ChemInform Abstract: Synthesis of Functionalized Isoquinolines via Sequential Cyclization/Cross-Coupling Reactions.

โœ Scribed by Xingxin Yu; Jie Wu


Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
41
Category
Article
ISSN
0931-7597

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Access to Functionalized Isoquinoline N-
โœ Qiuping Ding; Jie Wu ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB

## Abstract Electrophilic cyclization of 2โ€alkynylbenzaldoximes with various electrophiles leads to the formation of 4โ€iodoisoquinoline __N__โ€oxides or 4โ€bromoisoquinoline __N__โ€oxides under mild conditions. The reaction can be transferred to highly functionalized isoquinoline __N__โ€oxides __via__