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Synthesis of Functionalized Isoquinolines via Sequential Cyclization/Cross-Coupling Reactions

โœ Scribed by Yu, Xingxin; Wu, Jie

Book ID
126790620
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
521 KB
Volume
11
Category
Article
ISSN
1520-4766

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โœ Qiuping Ding; Jie Wu ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 202 KB ๐Ÿ‘ 1 views

## Abstract Electrophilic cyclization of 2โ€alkynylbenzaldoximes with various electrophiles leads to the formation of 4โ€iodoisoquinoline __N__โ€oxides or 4โ€bromoisoquinoline __N__โ€oxides under mild conditions. The reaction can be transferred to highly functionalized isoquinoline __N__โ€oxides __via__