## Abstract The conformational changes of poly‐__N__^ε^‐glutaryl‐L‐lysine (PGL) and poly‐__N__^ε^‐succinyl‐L‐lysine (PSL) in various salt solutions were studied by use of ORD and potentiometric titration measurements. The addition of alkali metal salts to the fully ionized PGL or PSL solution cause
Synthesis of poly-L-lysine and poly-L-lysyl albumin via ϵ,N-trifluoroacetyl-α,N-carboxy-L-lysine anhydride
✍ Scribed by Michael Sela; Ruth Arnon; Israel Jacobson
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1963
- Tongue
- English
- Weight
- 534 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0006-3525
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## Abstract Poly(__N__^ε^‐stearyl‐L‐lysine) and poly(__N__^ε^‐pelargonyl‐L‐lysine) were synthesized both by polymerization of __N__^ε^‐pelargonyl and __N__^ε^‐stearyl‐L‐lysine NCA and by acylation of poly(L‐lysine) with pelargonyl and stearyl chloride. This second route has proven to be very useful
Poly(trimethy1-L-lysine), [Lys(Mq)],, is converted from random coil to a-helix at about 1/30 of the NaC10, concentration required by poly(L-lysine), (Lys),. NaClO, generates turbidity in [Lys(Me),], at concentrations above that required for helix formation, and decreases turbidity above 1M NaC10,. T
The solvent-and pH-induced conformational changes are examined in order to investigate the influence of benzy 1 group. Polymer was prepared via N'-benzyloxycarbonyl, N'-benzyl-Nu-carboxy-clysine anhydride. The resulting poly(iV'-benzyloxycarbonyl, N'-benzyl-clysine) was obtained in a high yield and