A novel method for the efficientsynthesis phosphorodithioate DNA using H-phosphonothioate synthons is described. The 5'-DMT-nucleoside H-phosphonothioate monomers were prepared in two high yielding steps from commercially available phosphoramidites. This strategy for the synthesis of Hphosphonothioa
β¦ LIBER β¦
Synthesis of phosphorodithioate RNA by the H-phosphonothioate method
β Scribed by Charles H. Greef; Peter H. Seeberger; Marvin H. Caruthers; Graham Beaton; Danute Bankaitis-Davis
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 196 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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