Synthesis of Phosphonylated and Thiolated Indenones by Manganese(III)-Mediated Addition of Phosphorus- and Sulfur-Centered Radicals to 1,3-Diarylpropynones

✍ Scribed by Jun Zhou; Guang-Liang Zhang; Jian-Ping Zou; Wei Zhang

• Book ID: 102831423
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 510 KB
• Volume: 2011
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.201100486

✦ Synopsis

Abstract

Phosphorus‐ or sulfur‐centered radicals generated from the reaction of manganese(III) acetate with dialkyl phosphonates or arylthiols undergo selective additions to conjugated alkynes followed by cyclization and rearomatization to afford 2‐phosphonyl‐ or 2‐thioaryl‐substituted indenones in fair to good yields.