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Synthesis of Perfluoroalkyl-Substituted γ -Lactones and 4,5-Dihydropyridazin-3(2 H )-ones via DonorAcceptor Cyclopropanes

✍ Scribed by Gladow, Daniel; Reissig, Hans-Ulrich


Book ID
118759219
Publisher
John Wiley and Sons
Year
2012
Tongue
German
Weight
236 KB
Volume
95
Category
Article
ISSN
0018-019X

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## Abstract Optically active (perfluoroalkyl)‐oxazepin‐7‐ones were synthesized in two steps starting from ethyl perfluorobut‐2‐ynoate by direct addition of optically active amino alcohols __via__ intermolecular __Michael__ addition and lactone formation.