✦ LIBER ✦

Synthesis of optically pure steroid intermediate by the novel use of meso-compound

✍ Scribed by Shiro Terashima; Munehiko Nara; Shun-ichi Yamada

Publisher: Elsevier Science
Year: 1978
Tongue: French
Weight: 205 KB
Volume: 19
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)85646-x

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✦ Synopsis

When preparation of optically active synthetic intermediate is attempted by ordinary chemical resolution of racemic compound, maximum 50% of the resolution substrate can only be utilized for further synthetic scheme. Aiming to overcome this inefficiency, the authors have developed the new methodology 192) which recommends utilization of'syrrmetrically functionalized meso-compound as a resolution substrate in place of racemic modification.

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