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Synthesis of optically active 3-oxa-carbacyclin precursors featuring asymmetric Horner-Emmons reaction

✍ Scribed by Hans-Joachim Gais; Gerhard Schmiedl; Walter A Ball; Jörg Bund; Gunther Hellmann; Irene Erdelmeier

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
150 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis

i. Br. (FRG) Summery: An enantioselective synthesis of 5 is described. Asymmetric Iiorner-Nmmons reactions with the chiral phosphonate 6 are key steps in the synthesis of the allylic alcohols E-8 and E-11 from the ketones 5 and 9, respectively.

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