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Organocatalytic Regio- and Asymmetric C-Selective SNAr Reactions — Stereoselective Synthesis of Optically Active Spiropyrrolidone-3,3′-oxoindoles.

✍ Scribed by Marco Bella; Sara Kobbelgaard; Karl Anker Joergensen


Publisher
John Wiley and Sons
Year
2005
Weight
20 KB
Volume
36
Category
Article
ISSN
0931-7597

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Chemo- and stereoselective dirhodium(II)
✍ Takayuki Yakura; Akiharu Ueki; Tsuyoshi Kitamura; Kenji Tanaka; Masatake Nameki; 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 667 KB

Methyl (S)-(x-diazo-2,2-dimethyl-13-oxo-l,3-diox01ane-2-butanoate (4), upon treatment with dirhodium(II) tetmacetate in refluxing dichioromethane, gave methyl (1S,5S)-2,2-dimethyl-7-oxo-3,8dioxabicyclo[3.2.1 ]octane-l-carboxylate (5) via oxonium ylide formation/1,2-shift. On the other hand, a simila