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Synthesis of optically active 1,2,3-substituted-1,4,5,6-tetrahydro-7H-indolones

✍ Scribed by P. Nitti; G. Pitacco; A. Pizzioli; E. Valentin

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
559 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Trisubstituted 1,4,5,6,‐tetrahydro‐7__H__‐indolones are obtained in a one‐pot synthesis from conjugated nitroolefins and α‐ketoenamines derived from α‐amino esters and cyclohexane‐1,2‐dione. In some cases bicyclo[3.2.1]octan‐8‐one and 1,2‐oxazine N‐oxide derivatives are isolated.

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