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Synthesis of O-phosphorylated 1-substituted 2,2,2-trifluoroethanols, serine hydrolase inhibitors

✍ Scribed by A. Yu. Aksinenko; V. B. Sokolov; T. V. Goreva; G. F. Makhaeva


Book ID
106521498
Publisher
Springer
Year
2010
Tongue
English
Weight
215 KB
Volume
59
Category
Article
ISSN
1573-9171

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ChemInform Abstract: Asymmetric Synthesi
✍ H. PORAS; H. MATSUTANI; J. YARUVA; T. KUSUMOTO; T. HIYAMA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB πŸ‘ 1 views

Asymmetric Synthesis of 1-Alkoxy-2,2,2-trifluoroethanol Derivatives. -The title compounds such as (IV) and (VI), which may be useful as chiral building blocks, are prepared via trapping the intermediately formed optically active hemiacetals. The substitution of isopropanol in the chiral complex aga