## Abstract An amperometric method for the determination of the neurotoxic amino acid β‐__N__‐oxalyl‐L‐α,β‐diaminopropionic acid (β‐ODAP) using a screen printed carbon electrode (SPCE) is reported. The electrode material was bulk‐modified with manganese dioxide and used as a detector in flow inject
✦ LIBER ✦
Synthesis of Nα, Nβ-alkylated diaminopropionic acid analogs
✍ Scribed by M.E. Solomon; C.L. Lynch; D.H. Rich
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 203 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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p-N-Oxalyl-L-a$-diaminopropionic acid (P-L-ODAP) is thought to be the causative agent in lathyrism due to its neuroexcitatory and neurotoxic properties. We have recently reported that P-L-ODAF' is also gliotoxic at high concentrations (Bridges et al.: Brain Res 561:262, 1991). Evidence is now presen