β-isoxazolinone-alanine is involved in the biosynthesis of the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid
✍ Scribed by Fernand Lambein; Ongena Godelieve; Kuo Yu-Haey
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 674 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0031-9422
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📜 SIMILAR VOLUMES
p-N-Oxalyl-L-a$-diaminopropionic acid (P-L-ODAP) is thought to be the causative agent in lathyrism due to its neuroexcitatory and neurotoxic properties. We have recently reported that P-L-ODAF' is also gliotoxic at high concentrations (Bridges et al.: Brain Res 561:262, 1991). Evidence is now presen
## Abstract Experimental vibrational spectroscopic studies and density functional theory (DFT) calculations of the di‐amino acid peptide derivatives α‐ and β‐__N__‐acetyl‐L‐Asp‐L‐Glu have been undertaken. Raman and infrared spectra have been recorded for samples in the solid state. DFT simulations