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Synthesis of novel steroidal inhibitors of HIV-1 protease

✍ Scribed by James J. Harburn; Gabrielle C. Loftus; Brian A. Marples

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 1017 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(98)83048-2

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✦ Synopsis

The design and synthesis of potential steroidal HIV-1 protease inhibitors is described. Compounds derived from 11-amino-12-keto-cholanic acid derivatives show modest activity.

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