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Synthesis of Novel Pyrimido[4,5-c]pyridazines and 1,2-Dihydro-3a,7,9,9b-Tetraaza-cyclopenta[a]naphthalen-3-ones as Potent Inhibitors of Lymphocyte Specific Kinase (LCK)

✍ Scribed by Sabat, Mark; C. VanRens, John; A. Brugel, Todd; Maier, Jennifer; J. Laufersweiler, Matthew; Golebiowski, Adam; Berberich, Steve; De, Biswanath


Book ID
121881181
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
187 KB
Volume
68
Category
Article
ISSN
0385-5414

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✍ Raafat M. Shaker; Kamal U. Sadek; Ebtisam A. Hafez; Mohamed Abd Elrady 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 33 KB

## Abstract Efficient and direct protocols for the regioselective synthesis of the title compounds (IV) and (IX), resp., using multicomponent reactions of 5‐aminouracil (II) are given.