✦ LIBER ✦

Synthesis of novel phosphonopeptide derivatives and their biological activity

✍ Scribed by Qing Dai; Ruyu Chen

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 140 KB
Volume: 8
Category: Article
ISSN: 1042-7163
DOI: 10.1002/(sici)1098-1071(1997)8:3<279::aid-hc12>3.0.co;2-o

No coin nor oath required. For personal study only.

✦ Synopsis

In order to search for novel herbicides with high activity and selectivity, a series of N-p-toluenesulfonyl phosphonopeptide derivatives has been designed and synthesized by the condensation reaction of diphenyl ␣-aminoalkylphosphonates and 1-p-toluenesulfonamido-acetyl chloride. Their structures were confirmed by 1 H NMR spectroscopy and elemental analyses. The results of bioassay showed that some of these compounds possess potential anti-TMV (Tobacco Mosaic Virus) activity.

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