✦ LIBER ✦

Synthesis and Biological Activity of Sarcodictyins

✍ Scribed by K. C. Nicolaou; Sanghee Kim; Jeffrey Pfefferkorn; Jinyou Xu; Takashi Ohshima; Seijiro Hosokawa; Dionisios Vourloumis; Tianhu Li

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 108 KB
Volume: 37
Category: Article
ISSN: 0044-8249
DOI: 10.1002/(sici)1521-3773(19980605)37:10<1418::aid-anie1418>3.0.co;2-5

No coin nor oath required. For personal study only.

✦ Synopsis

A new class of potential antitumor agents with a taxol-like mechanism of action is presented by the sarcodictyins 1. Modification of the reported syntheses of sarcodictyins permitted the preparation of additional derivatives, the biological properties of which are highly dependent upon the structure.

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