Synthesis of novel C2-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes
β Scribed by Bin Fu; Da-Ming Du; Jianbo Wang
- Book ID
- 108283699
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 317 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0957-4166
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Novel C 2 -symmetric tetradentate bis-oxazoline ligands were efficiently prepared from a-amino acids, 1,2-amino alcohols and 1,2-or 1,3-diacids. The ligands were employed in the titanium-catalyzed addition of diethylzinc to benzaldehyde, and depending on conditions used, moderate to high enantiosele
The C 2 -symmetrical bis-b-amino alcohols 1-6 were prepared and especially attention is focused on bridges, which link the two b-amino alcohol units. These ligands have been applied as chiral catalysts in the asymmetric addition of diethylzinc to aldehydes. sec-Alcohols have been obtained in good yi