𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of novel C2 and C2–C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents

✍ Scribed by Ahmed Kamal; O. Srinivas; P. Ramulu; G. Ramesh; P.Praveen Kumar

Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
182 KB
Volume
13
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design and synthesis of novel chrysene-l
Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents
✍ Ahmed Kamal; G. Ramesh; P. Ramulu; O. Srinivas; Tasneem Rehana; G. Sheelu 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 183 KB

Chrysene-linked pyrrolobenzodiazepine hybrids have been prepared that posses cytotoxicity in some cancer cell lines. They also exhibit promising DNA-binding affinity and this is supported by molecular modeling studies.

ChemInform Abstract: Synthesis of Sequen
ChemInform Abstract: Synthesis of Sequence-Selective C8-Linked Pyrrolo(2,1-c)(1,4) benzodiazepine DNA Interstrand Cross-Linking Agents.
✍ D. E. THURSTON; D. S. BOSE; A. S. THOMPSON; P. W. HOWARD; A. LEONI; S. J. CROKER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

Synthesis of Sequence-Selective C8-Linked Pyrrolo(2,1-c)(1,4) benzodiazepine DNA Interstrand Cross-Linking Agents. -In order to construct the key A-ring fragments (VI), a versatile convergent approach is developed to join two units of vanillic acid (I) with α,ω-dihaloalkanes (II). The "amino-thioac