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Synthesis of novel aromatic analogues of 12-HETE

✍ Scribed by Ali Hachem; Yves Le Floc'h; René Gree; Yves Rolland; Serge Simonet; Tony Verbeuren


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
118 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


New mono-and diaromatic analogues of the arachidonic acid metabolite 12-HETE have been prepared using versatile strategies. The easily accessible monoacetal of isophtalaldehyde 3 was developed as a key intermediate for these syntheses.


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