The synthesis of 13-azaprostacyclin methyl ester 13 in ten steps from the readily available 2-exo-bromo-3-endo-methoxybicyclx3.2.0]heptan-6one 1 is described. --Inhibition of platelet aggregation and vasodilation are two well recognised properties of prostacyclin and based on these effects it has g
Synthesis of 12-azaprostacyclin analogues
β Scribed by F. Cassidy; R.W. Moore; G. Wootton; K.H. Baggaley; G.R. Geen; L.J.A. Jennings; A.W.R. Tyrrell
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 177 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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