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Synthesis of Novel 8,9-Dihydro-5 H -pyrimido[4,5- e ][1,4]diazepin-7(6 H )-ones

✍ Scribed by Xiang, Jinbao; Wen, Dongsheng; Xie, Hongxiang; Dang, Qun; Bai, Xu


Book ID
121382034
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
238 KB
Volume
12
Category
Article
ISSN
1520-4766

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## Abstract magnified image A series of tricyclic 7,8,10,11‐tetrahydro‐5__H__‐benzo[__e__]pyrimido[4,5‐__b__][1,4]diazepin‐9(6__H__)‐ones were prepared in moderate to high yields using TFA‐promoted iminium‐cyclization reactions of 3‐(6‐(butylamino)‐4‐chloropyrimidin‐5‐ylamino)cyclohex‐2‐enones and