𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of novel 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines as potential protein kinase inhibitors

✍ Scribed by Marko P. Sušnik; Michael Schnürch; Marko D. Mihovilovic; Kurt Mereiter; Peter Stanetty


Book ID
106214108
Publisher
Springer Vienna
Year
2008
Tongue
English
Weight
384 KB
Volume
140
Category
Article
ISSN
0026-9247

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of 2-amino-4-oxo-5-substituted
✍ Aleem Gangjee; Hiteshkumar D. Jain; Jaclyn Phan; Roy L. Kisliuk 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 59 KB

A series of ten novel 2-amino-4-oxo-5-[(substitutedbenzyl)thio]pyrrolo [2,3-d]pyrimidines 2-11 were synthesized as potential inhibitors of thymidylate synthase and as antitumor agents. The analogues contain various electron withdrawing and electron donating substituents on the benzylsulfanyl ring of

Synthesis of novel, nonclassical 2-amino
✍ Aleem Gangjee; Nauzer P. Dubash; Roy L. Kisliuk 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 66 KB

## Abstract A novel series of 14 nonclassical 6‐substituted pyrrolo[2,3‐__d__]pyrimidines **2a ‐ 2n** were designed as potential inhibitors of thymidylate synthase, based on previously reported 2‐amino‐4‐oxopyrrolo[2,3‐__d__]‐pyrimidines **1a** and **1b**. The synthesis of the target compounds **2a