## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of novel 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines as potential protein kinase inhibitors
✍ Scribed by Marko P. Sušnik; Michael Schnürch; Marko D. Mihovilovic; Kurt Mereiter; Peter Stanetty
- Book ID
- 106214108
- Publisher
- Springer Vienna
- Year
- 2008
- Tongue
- English
- Weight
- 384 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0026-9247
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A series of ten novel 2-amino-4-oxo-5-[(substitutedbenzyl)thio]pyrrolo [2,3-d]pyrimidines 2-11 were synthesized as potential inhibitors of thymidylate synthase and as antitumor agents. The analogues contain various electron withdrawing and electron donating substituents on the benzylsulfanyl ring of
## Abstract A novel series of 14 nonclassical 6‐substituted pyrrolo[2,3‐__d__]pyrimidines **2a ‐ 2n** were designed as potential inhibitors of thymidylate synthase, based on previously reported 2‐amino‐4‐oxopyrrolo[2,3‐__d__]‐pyrimidines **1a** and **1b**. The synthesis of the target compounds **2a