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Synthesis of Novel 2,5-Dihydro-1,5,2-diazaphosphinines from Primary Enamine Phosphonates and from Alkyl Phosphonates.

โœ Scribed by Francisco Palacios; Ana M. Ochoa de Retana; Sergio Pascual; Rafael Lopez de Munain; Julen Oyarzabal; Jose M. Ezpeleta


Book ID
101977182
Publisher
John Wiley and Sons
Year
2005
Weight
30 KB
Volume
36
Category
Article
ISSN
0931-7597

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A simple route to novel 2,5-dihydro-1,5,
โœ Francisco Palacios; Ana M Ochoa de Retana; Sergio Pascual; Rafael Lรณpez de Munai ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 83 KB

A simple method for the preparation of phosphorus-containing pyrimidine analogues such as 4,6-disubstituted-2ethoxy-2,5-dihydro-1,5,2-diazaphosphinine 2-oxides 5 from primary enamine phosphonates and nitriles is described. A similar strategy is used for the synthesis of the corresponding 4,6-difluor