A simple method for the preparation of phosphorus-containing pyrimidine analogues such as 4,6-disubstituted-2ethoxy-2,5-dihydro-1,5,2-diazaphosphinine 2-oxides 5 from primary enamine phosphonates and nitriles is described. A similar strategy is used for the synthesis of the corresponding 4,6-difluor
โฆ LIBER โฆ
A Simple Route to Novel 2,5-Dihydro-1,5,2-diazaphosphinines from Primary Enamine Phosphonates.
โ Scribed by Francisco Palacios; Ana M. Ochoa de Retana; Sergio Pascual; Rafael Lopez de Munain
- Book ID
- 101939450
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Easily accessible 2โbenzoylaminoโ3,3โdichloroacrylonitrile, when treated successively with primary amines, phosphorus pentachloride, sulfur dioxide, and various Nโ or Sโnucleophiles, furnishes the corresponding derivatives of 1,2โdihydroโ2ฮป^5^โ[1,3]oxazolo[5,4โ__d__][1,3,2]diazaphosphin