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Synthesis of Non-immunosuppressive Cyclophilin-Binding Cyclosporin A Derivatives as Potential anti-HIV-1 Drugs.

✍ Scribed by Serge Mignani; et al. et al.


Publisher
John Wiley and Sons
Year
2004
Weight
51 KB
Volume
35
Category
Article
ISSN
0931-7597

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Synthesis of new uracil non-nucleoside d
✍ Farag A. El-Essawy; Nasser R. El-Brollosy; Erik B. Pedersen; Claus Nielsen πŸ“‚ Article πŸ“… 2003 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 58 KB

## Abstract 6‐(2‐Phenylethyl) and 6‐cyclohexyl 5‐cyanouracils (**1a,b**) were synthesized and reacted with chloromethyl ethyl ether, benzyl chloromethyl ether, chloromethyl methyl sulfide and (2‐acetoxyethoxy)methyl bromide. New uracil analogues of (__S__)‐DHPA were synthesized by reaction of compo