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Synthesis of Novel Uracil Non-Nucleoside Derivatives as Potential Reverse Transcriptase Inhibitors of HIV-1

โœ Scribed by Nasser R. El-Brollosy; Omar. A. Al-Deeb; Ali A. El-Emam; Erik B. Pedersen; Paolo La Colla; Gabriella Collu; Giuseppina Sanna; Roberta Loddo


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
407 KB
Volume
342
Category
Article
ISSN
0365-6233

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Synthesis of 2-Methylsulfanyl-1H-imidazo
โœ Yasser M. Loksha; Mahmoud A. El-Badawi; Ahmed A. El-Barbary; Erik B. Pedersen; C ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 158 KB ๐Ÿ‘ 1 views

## Abstract ฮฑโ€Aminoketone hydrochlorides **2aโ€”d** were synthesized by Dakinโ€West reaction from __L__โ€phenylalanine and __L__โ€cyclohexylalanine followed by hydrolysis in acidic medium. Treatment of **2aโ€”d** with aqueous potassium thiocyanate afforded 1, 3โ€imidazoleโ€2โ€thiones **3aโ€”d** which were alky