Synthesis of Nitrolipids. All Four Possible Diastereomers of Nitrooleic Acids: ( E )- and ( Z )-, 9- and 10-Nitro-octadec-9-enoic Acids
β Scribed by Woodcock, Steven R.; Marwitz, Adam J. V.; Bruno, Paulo; Branchaud, Bruce P.
- Book ID
- 127341026
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 63 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1523-7060
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A stereoselective synthesis of 4, a possible biosynthetic precursor of lipoxins, is reported. A pathway is suggested by which 4 can give rise to the biologically active lipoxins 1 and 2. In 1984 Serhan, Hamberg and Samuelsson reported that human leukocytes convert 15(S)-