Synthesis of new pyridazinone derivatives as platelet aggregation inhibitors
✍ Scribed by Sridhar Thota; Ranju Bansal
- Book ID
- 105771000
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 288 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1054-2523
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📜 SIMILAR VOLUMES
In a search for the inhibitors of platelet aggregation, certain coumarin derivatives were synthesized and evaluated for antiplatelet activity against thrornbin(Thr)-, arachidonic acid(AA)-, collagen(Co1)-, and platelet-activating-factor(PAF)-induced aggregation in washed rabbit platelets. These comp
## Abstract Several 3(2__H__)‐pyridazinones with amino groups at the 5‐position of the pyridazine nucleus have been prepared. The 6‐aryl‐5‐halo‐3(2__H__)‐pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5‐alkylamino‐3(2__H__)‐pyridazinones, which were tested as