✦ LIBER ✦

Pyridazines. XV. Synthesis of 6-aryl-5-amino-3(2H)-pyridazinones as potential platelet aggregation inhibitors

✍ Scribed by Isabel Estevez; Enrique Raviña; Eddy Sotelo

Publisher: Journal of Heterocyclic Chemistry
Year: 1998
Tongue: English
Weight: 543 KB
Volume: 35
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570350634

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Several 3(2__H__)‐pyridazinones with amino groups at the 5‐position of the pyridazine nucleus have been prepared. The 6‐aryl‐5‐halo‐3(2__H__)‐pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5‐alkylamino‐3(2__H__)‐pyridazinones, which were tested as platelet aggregation inhibitors.

📜 SIMILAR VOLUMES

ChemInform Abstract: Pyridazines. Part 1

ChemInform Abstract: Pyridazines. Part 15. Synthesis of 6-Aryl-5-amino-3(2H)-pyridazinones as Potential Platelet Aggregation Inhibitors.

✍ Isabel Estevez; Enrique Ravina; Eddy Sotelo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Synthesis of 6-Aryl-5-amino-3(2H)pyridazinones as Potential Platelet Aggregation Inhibitors. -Several 3(2H)-pyridazinones (III), (V), (VII), (IX), (XI) with amino groups at the 5-position are prepared starting from mucochloric or mucobromic acids (I) and tested as platelet aggregation inhibitors.

Pyridazines. Part 28. 5-Alkylidene-6-phe

Pyridazines. Part 28. 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a New Family of Platelet Aggregation Inhibitors.

✍ Eddy Sotelo; Nuria Fraiz; Matilde Yanez; Reyes Laguna; Ernesto Cano; Jose Brea; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB

## Abstract For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract: Synthesis of 4,5-Fu

ChemInform Abstract: Synthesis of 4,5-Functionalized-2-methyl-6-(substituted aryl)-3(2H)- pyridazinones: A New Group of Potent Platelet Aggregation Inhibitors.

✍ V. DAL PIAZ; G. CICIANI; M. P. GIOVANNONI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis of Some Thiazolo[3,2-b]-1,2,4-

Synthesis of Some Thiazolo[3,2-b]-1,2,4-triazole-5(6H)-ones as Potential Platelet Aggregation Inhibitors

✍ Birsen Tozkoparan; Hülya Akgün; Mevlüt Ertan; Klaus Rübsemann 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB 👁 1 views

Pyridazines and Condensed Pyridazines: R

Pyridazines and Condensed Pyridazines: Routes for Synthesis of 3-Amino-5-aryl-2,5-dihydro-pyridazine, 10aH-Pyridazino[1,6-a]quinazoline and Thieno[3,4-d]pyridazinone.

✍ Suzan Ibrahim Aziz; Hany Fakhry Anwar; Morsy Ahmed El-Apasery; Mohamed Hilmy Eln 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Studies with pyridazines and condensed p

Studies with pyridazines and condensed pyridazines: Routes for synthesis of 3-amino-5-aryl-2,5-dihydro-pyridazine, 10aH-pyridazino[1,6-a]quinazoline and thieno[3,4-d]pyridazinone

✍ Suzan Ibrahim Aziz; Hany Fakhry Anwar; Morsy Ahmed El-Apasery; Mohamed Hilmy Eln 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 388 KB 👁 1 views

## Abstract magnified image Novel routes to 3‐aminopyridazines, 10a__H__‐pyridazino[1,6‐__a__]quinazoline and, thieno[3,4‐__d__]pyridazine utilizing the reaction of 2‐oxobutanal‐1‐arylhydrazones **3a,b** with α,β‐unsaturated nitriles are described. Condensation of **3** with ethyl cyanoacetate aff