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Synthesis of New Chiral Hydroxy Oxazolines and Their Use in the Catalytic Asymmetric Phenyl Transfer to Aldehydes.

✍ Scribed by Carsten Bolm; Frank Schmidt; Lorenzo Zani


Publisher
John Wiley and Sons
Year
2005
Weight
17 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract Optically active new pyridyl alcohols **1–4**, which can be easily synthesized by the reaction of (+)‐camphor or (βˆ’)‐menthone with lithiated pyridine derivatives, were applied as chiral ligands in the asymmetric addition of diethylzinc to aldehydes. Good yields with up to 94.0%enantiome