Synthesis of New Chiral Aliphatic Amino Diselenides and Their Application as Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes
✍ Scribed by Braga, Antonio L.; Paixão, Marcio W.; Lüdtke, Diogo S.; Silveira, Claudio C.; Rodrigues, Oscar E. D.
- Book ID
- 118141682
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 104 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
The application of a new type of polymer anchored chiral amino-oxazolinyl ligand as catalyst for the enantioselective addition of diethylzinc to aldehydes is reported. The catalyst is effective at a low ligand concentration and can be reused with minimal loss of activity.
## Abstract For Abstract see ChemInform Abstract in Full Text.
Optically active amino thioacetate derivatives of (+l-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.