## Abstract For Abstract see ChemInform Abstract in Full Text.
New polymer anchored chiral amino oxazolines as effective catalysts for enantioselective addition of diethylzinc to aldehydes
β Scribed by Nadim S Shaikh; Vishnu H Deshpande; Ashutosh V Bedekar
- Book ID
- 104251544
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 75 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The application of a new type of polymer anchored chiral amino-oxazolinyl ligand as catalyst for the enantioselective addition of diethylzinc to aldehydes is reported. The catalyst is effective at a low ligand concentration and can be reused with minimal loss of activity.
π SIMILAR VOLUMES
Optically active amino thioacetate derivatives of (+l-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.
Optically active ferrocenyl amino alcohols have been prepared from commercially available L-alaninol, L-leucinol and L-valinol. They have been utilized as chiral ligands in the catalytic addition of diethylzinc to aldehydes. The influence of the substituents on the stereogenic centers of the ligand