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Synthesis of new amidophosphates containing an adamantyl fragment under microwave irradiation

โœ Scribed by L. I. Minaeva; L. S. Patrikeeva; B. S. Orlinson; I. A. Novikov; M. M. Kabachnik; I. P. Beletskaya


Book ID
111465264
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
511 KB
Volume
46
Category
Article
ISSN
1070-4280

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7-Chloromethyl-6-nitro-5H-thiazolo[3,2-a]pyrimidin-5-one (2) is obtained by cyclocondensation of 2aminothiazole with ethyl 4-chloroacetoacetate. This product was shown to react with various nitronate or malonate anions under microwave irradiation to give potentially bioactive 6-nitro-5H-thiazolo[3,2