Synthesis of N-Substituted Carbonylamino-1,2,3,6-tetrahydropyridines as Potential Anti-Inflammatory Agents
✍ Scribed by Ghaffari, Mohammad A.; Ardley, Tiffany W.; Gangapuram, Madhavi; Redda, Kinfe K.
- Book ID
- 120404590
- Publisher
- Taylor and Francis Group
- Year
- 2011
- Tongue
- English
- Weight
- 208 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0039-7911
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## Abstract Fourteen novel __N__‐(substituted phenylcarbonylamino)‐4‐ethyl‐1,2,3,6‐tetrahydropyridines **9** were synthesized in fair to good yields. 4‐Ethylpyridine **5** reacted with __O__‐mesitylenesulfonylhydroxylamine (__O__‐MSH) **4** to furnish __N__‐amino‐4‐ethylpyridinium mesitylenesulfona
## Abstract magnified image N‐Benzoylamino‐1,2,3,6‐tetrahydropyridines **9a‐q** were synthesized from 4‐substituted pyridines in four steps. Amination of pyridines was carried out to prepare intermediate N‐aminopyridinium mesylates using mesytelenesulfonyl hydroxmate (MSH) as aminating agent. N‐am
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