𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of N-benzoylamino-1,2,3,6-tetrahydropyridine derivatives as potential anti-inflammatory agents

✍ Scribed by Bereket Mochona; Kinfe K. Redda

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
302 KB
Volume
44
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

magnified image

N‐Benzoylamino‐1,2,3,6‐tetrahydropyridines 9a‐q were synthesized from 4‐substituted pyridines in four steps. Amination of pyridines was carried out to prepare intermediate N‐aminopyridinium mesylates using mesytelenesulfonyl hydroxmate (MSH) as aminating agent. N‐aminopyridinium mestylates reacted with appropriately substituted acyl chlorides to form N‐ylides as stable crystalline solids. Partial reduction of N‐ylides with mild reducing agent afforded N‐benzoylamino‐1,2,3,6‐tetrahydropyridines in fair to good yields.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of N-Benz
ChemInform Abstract: Synthesis of N-Benzoylamino-1,2,3,6-tetrahydropyridine Derivatives (I) as Potential Antiinflammatory Agents
✍ Bereket Mochona; Kinfe K. Redda 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis of N-(substituted phenylcarbon
Synthesis of N-(substituted phenylcarbonylamino)-4-ethyl-1,2,3,6-tetrahydropyridines as potential nonsteroidal anti-inflammatory agents
✍ Kyoung Jin P. Yoon; Bala Kode; Lynneice Bowen; Kinfe K. Redda 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 95 KB

## Abstract Fourteen novel __N__‐(substituted phenylcarbonylamino)‐4‐ethyl‐1,2,3,6‐tetrahydropyridines **9** were synthesized in fair to good yields. 4‐Ethylpyridine **5** reacted with __O__‐mesitylenesulfonylhydroxylamine (__O__‐MSH) **4** to furnish __N__‐amino‐4‐ethylpyridinium mesitylenesulfona