Several new 3-(indazol-3-yl)-quinazolin-4(3H)-one and 3-(indazol-3-yl)-benzotriazin-4(3H)-one derivatives 5 and 6 were synthesized and tested for their in vitro antiproliferative activity against Raji, K562, and K562-R cell lines. The pharmacological screening showed that some 2, 6, or 7-substituted
Synthesis of N-3[4-(4-Chlorophenyl) thiazole-2-yl]-2-(aminomethyl)quinazoline-4(3H)-one and Their Derivatives for Antitubercular Activity.
β Scribed by Shashikant R. Pattan; V. V. Krishna Reddy; F. V. Manvi; B. G. Desai; A. R. Bhat
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Some novel substitutedβ3β{[(1__E__)β(substitutedβ2βfuryl)βmethylene]amino}quinazolinβ4(3__H__)βone (**5, 6, 7**) **aβf** were synthesized by a multiβstep process. These synthesized compounds are characterized by various spectroscopic techniques and evaluated for their antitubercular and
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